Amanita Design rocks! They make flash-based games, animations and websites for people like Nike & the BBC. Their point and click flash-based games are really fun and the animation is gorgeous! The two stand-out games for them have to be the Samorost series, (see below) and the preview to their newest game, Machinarium.
Play Samorost HERE. (I just spent my breakfast playing it and was thoroughly entertained!)